Research Dosing

Semax

Semax is a synthetic peptide that is an analog of adrenocorticotropic hormone (ACTH). It has been studied for its neuroprotective, cognitive-enhancing, and antidepressant effects. Semax stimulates the release of brain-derived neurotrophic factor (BDNF), a protein that promotes neuron growth and survival, and modulates neurotransmitter levels including dopamine, serotonin, and norepinephrine. It offers nootropic, neuroprotective, and neurorestorative benefits.

Benefits

  • Memory enhancement: Participants using Semax made 31% more correct responses than the control group on memory tests
  • Neu
  • oprotection: Shields neurons from stroke, trauma, or neurodegenerative disease damage
  • Antidepressant effects: Reduces anxiety and depression in animal studies
  • Supports neuron survival and promotes synaptic growth and neuroplasticity
  • Helps neurons adapt to injury or environmental change
  • Protects the optic nerve and may be helpful for related disorders
  • Improves trophic supply of the brain (supports brain network connectivity)
  • May help manage ADHD symptoms
  • Inhibits enzymes that degrade enkephalins and regulatory peptides
  • May support recovery from opioid or alcohol withdrawal
  • Shows improvement in non-proliferative diabetic neuropathy
  • Potential for pain relief

Possible Side Effects

  • Headache
  • Mild dizziness or light-headedness
  • Very rare risk of slight increase in blood sugar levels
  • Injection site reaction (redness, swelling, and/or itching)

Warnings and Precautions

Semax modulates central nervous system signaling pathways, including dopaminergic, serotonergic, and neurotrophic (e.g. BDNF-related) mechanisms. Use caution in individuals with a history of:

  • Anxiety disorders
  • Panic disorder
  • Bipolar disorder (including hypomania or mania)
  • Psychotic disorders or schizophrenia

Potential adverse neuropsychiatric effects may include agitation, irritability, restlessness, or insomnia. Discontinue use if clinically significant psychiatric symptoms emerge or worsen.

Contraindications

  • Do not use if you determine that you are hypersensitive to Semax- this is an indication of an allergic reaction
  • Do not use if pregnant or breastfeeding
  • Avoid in individuals with endocrine instability
  • Use caution if you have a severe psychiatric disorder (particularly active psychosis, manic episodes, or uncontrolled anxiety)- the stimulatory/neuroactive effects could worsen mood/psychiatric state
  • Safety profile is not well established in children and pediatric use should be avoided

SEMAX: 10MG – CYCLING, DOSING CONSIDERATIONS, ADMINISTRATION

6-8 week cycle followed by 6-8 week washout period

Morning dosing

May be taken with or without food

Subcutaneous or Nasal Administration*

DOSING

Standard Protocol

Add 3mL (300 units) of BAC water

Weeks 1-2: 10-15 units, 1x/day, 5-7 days/week

Weeks 3-4: 15 units, 1x/day, 5-7 days/week

Weeks 5-8: 30 units, 1x/day, 5-7 days per week

  • Nasal Formulation Instructions COMING SOON