Research Dosing

AOD 9604

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Go to the Prep & Injection Guide for proper reconstitution, syringe sizing, and injection protocols. Mistakes here can compromise your research.

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AOD-9604 (Anti-Obesity Drug 9604)

AOD-9604 is a fragment of the human growth hormone developed for the treatment of obesity. It is designed to mimic the fat-burning properties of hGH without its muscle-building effects or the common side effects.

This is achieved through Tyrosine (TYR), a portion of the amino acid sequence responsible for fat reduction and tissue repair. It mimics the effects of hGH on lipid metabolism without promoting growth or triggering pro-diabetic effects.

Where GLP-1 agonists suppress appetite and influence insulin secretion, AOD-9604 inhibits lipoprotein lipase activity in fat tissue, stimulating lipolysis in adipocytes. It specifically targets areas of the body with high fat deposits, preventing the conversion of carbohydrates into triglycerides and fatty acids and blocking the process of lipogenesis.

AOD-9604 can be particularly useful when stacked with GLP-1s to combat plateaus and target stubborn fat that diet and exercise alone may not eliminate.

Additional Benefits

  • Increases metabolism
  • Stimulates lipolysis
  • Inhibits lipogenesis (formation of fat cells)
  • Promotes bone and cartilage repair
  • Improves bone strength
  • Does not impact blood sugar levels
  • Enhances collagen production and skin elasticity
  • Possesses anti-inflammatory properties (beneficial for arthritis)
  • Enhances joint flexibility and mobility
  • Prevents medication-related muscle-wasting

Possible Side Effects

  • Injection site reactions (redness, swelling, itching)
  • Headache
  • Fatigue
  • Dizziness
  • Cough
  • Chest tightness or constriction
  • Heart palpitations
  • Cold-like symptoms

Contraindications

Do not use AOD-9604 if you are pregnant or breastfeeding.

Preparation & Dosing

AOD-9604: 5 mg vial
Mix with 3 mL (300 units) of acetic acid reconstitution solution (not BAC)
Subcutaneous Administration

Note: It takes approximately 3 weeks to reach steady state levels in the system. Tangible effects may not be noticeable during this time.

Typical Cycle Duration

  • Cycles vary
  • Typically 3 months
  • 6–8 week or up to 6-month cycles are also common
  • 8–12 week cycle followed by 8–12 week washout period
  • Dose 5 days per week, followed by 2 consecutive rest days
  • Take dose immediately after wakeup and maintain fast for at least one hour after injection

Dosing Options

Standard Protocol (General Benefits / Longer Cycles)
18 units = 300 mcg
Take 18 units (300 mcg) once daily

  • First thing in the morning on an empty stomach
  • Remain fasted for 3–4 hours after injection if possible
  • Suggested schedule: 20 days on, 10 days off

Weight Loss Protocol (Maximum Fat Loss / Shorter Cycles)
15 units = 250 mcg
Take 15 units (250 mcg) twice daily

  • Once in the morning (fasted)
  • Once at least 1 hour after dinner

Stacking Suggestions

AOD-9604 stacks well with several peptides, especially for regenerative or fat-loss goals. Common combinations include:

  • GLP-1s – to break through weight loss plateaus
  • BPC-157
  • TB-500
  • Ipamorelin
  • Sermorelin
  • CJC No DAC

AOD-9604 and GLP-1s
It is strongly recommended that individuals taking GLP-1 medications who still have 30+ pounds to lose, or who are slow responders or have plateaued, consider adding AOD-9604 to their protocol for a minimum of 3 months. The combination may significantly improve outcomes.