Research Dosing

HCG

🔴 IMPORTANT: Read This Before Proceeding With Dosing
Go to the Prep & Injection Guide for proper reconstitution, syringe sizing, and injection protocols. Mistakes here can compromise your research.

👉 Click here to read the Prep & Injection Guide

HCG (Human Chorionic Gonadotropin)

HCG for Men

Commonly prescribed to help address the symptoms of hypogonadism, low testosterone, and infertility. Testosterone deficiency is typically accompanied by fatigue, stress, a low sex drive, and depression. HCG increases testosterone and sperm, which can help reduce infertility and restore sexual desire/drive. Perhaps unexpectedly, HCG may be able to minimize or prevent such side effects from the consumption of anabolic steroids as gonad shrinkage, dropping sperm count, and infertility.

In men, HCG acts like luteinizing hormone (LH). LH stimulates Leydig cells in the testicles, which results in the production of testosterone. LH stimulates production of sperm within structures in the testicles (the “seminiferous tubules”). As HCG stimulates the testicles to produce testosterone and sperm, the testicles grow in size over time.

HCG for Women

A glycoprotein that is produced during pregnancy and is produced by the placenta. It plays a vital role in maintaining pregnancy and supporting fetal development. It thickens the uterine lining, and signals the body to cease menstruation and create more estrogen and progesterone.

HCG injections can increase the chances of becoming pregnant when used in combination with either IVF (in vitro fertilization) or IUI (intrauterine insemination). It works by inducing ovulation (the release of an egg by the ovaries). If you have a history of infertility, monitoring HCG levels early on in the pregnancy can determine if a successful pregnancy has occurred.

A shot of HCG is considered a trigger shot, and once given, triggers ovulation within 36 hours.
The HCG hormone may increase the chances of multiple pregnancies, which may be a high risk to both the mother and babies. Discontinue HCG immediately after conception.

Side Effects

  • Headache
  • Fatigue
  • Restlessness and/or irritability
  • Tenderness or swelling in the breasts
  • Swelling, water retention
  • Depression
  • Gynecomastia (growth of male breasts)

Rare but serious or life-threatening conditions may include:

  • Blood clots – signs include pain, warmth, redness, extreme dizziness, severe headache, numbness, tingling in extremities, confusion
  • Ovarian Hyperstimulation Syndrome (OHSS) – symptoms include severe pelvic pain, nausea and vomiting, diarrhea, difficulty breathing, stomach swelling, leg or hand swelling, rapid weight gain, reduced urine
  • Early puberty in young boys

Contraindications

Do not take if you have ever had an allergic reaction to HCG, or if you have:

  • Early (precocious) puberty
  • Hormone-related cancer (e.g., prostate cancer)
  • Cancer or tumor of the breast(s), ovary, or uterus
  • Certain types of ovarian cysts
  • Uncontrolled thyroid or adrenal dysfunction
  • Cancer or tumor of the hypothalamus or pituitary gland
  • Vaginal bleeding of unknown cause
  • If you are pregnant

Consult a doctor before using HCG if you have:
Thyroid/adrenal disorder, ovarian cyst, unexplained vaginal bleeding, heart disease, kidney disease, epilepsy, migraines, or asthma.

HCG: 1,000 IU’s

Cycle will depend on application

Dose in the morning

Does not need to be taken while fasted

Subcutaneous or Intramuscular Administration

RECONSTITUTION: 1,000iu’s

Mix HCG 1,000iu’s with 1mL (100 units) of BAC water

LOW DOSE PROTOCOL: 1,000iu’s

Mimics Natural LH Levels

250-500ius, 3x/week

250ius = 25 units

375ius = 38 units

500ius= 50 units

Some users experience temporary heart palpitations or anxiety due to LH release — this usually fades with continued use.

HCG: 5,000 IU’s

8-16 week protocol followed by 8-16 week washout period

HCG has a 36-hour half-life, making daily dosing unnecessary

Make an effort to dose on the same days and times as often as possible

Morning dosing preferred

Subcutaneous or Intramuscular Administration

RECONSTITUTION

Mix with 2mL (200 units) of BAC water

Standard Protocol: 1,500iu’s/week

To maintain intratesticular testosterone during exogenous testosterone therapy and support fertility preservation

20 units (500iu’s), 1x/day, 3 days per week, for 12 weeks

High Dose Protocol: 1,000-2,500iu’s/injection, 3x/week subcutaneously

To reactivate testosterone production after prolonged anabolic steroid use or severe hypogonadotropic hypogonadism

Weeks 1-4: 60 units (1,500iu’s), 3x per week, for 4 weeks

Weeks 4-8: 80 units (2,000iu’s), 3x per week, for 4 weeks

Weeks 9-12: 40 units (1,000iu’s), 3x per week, for 4 weeks

Low Dose Protocol

Mimics natural LH levels

250–500iu’s, 3x per week

10 units (250iu’s), 3x per week

15 units (375iu’s), 3x per week

20 units (500iu’s), 3x per week

Standard TRT Support Dosage

Helps maintain testicular function without suppressing testosterone therapy

500–1,500 IUs, 1–3x per week

  • Helps maintain testicular function without suppressing testosterone therapy

Bodybuilding Post-Cycle Protocol

  • 1,000–3,000 IUs, 1–3x per week

High Dose Fertility/Restoration Protocol

  • 1,500–5,000 IUs, 2–3x per week

Ovulation Trigger (women)

  • 200 units. Load two 100 unit syringes or four 50 unit syringes, depending on preference. 5,000 IUs as a one-time injection

Stacking & Pairing Suggestions

  • Testosterone Replacement Therapy (TRT) – Maintains testicular size and fertility during TRT
  • Clomid (Clomiphene Citrate) – Enhances natural testosterone production, ideal for post-cycle use
  • Aromatase Inhibitors (e.g., Arimidex) – Helps regulate estrogen while on HCG
  • BPC-157 or TB-500 – Supports injury healing and recovery during hormone therapy
  • PT-141 or Kisspeptin – Boosts libido and sexual function when paired with HCG